Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.45 |
| ▸ | ABAT | P80404 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11032181 | 0.77 | KMT2A (0.51) | ALDH1A1HPGDALDH5A1ABATMAPT | |
| SCHEMBL7272198 | 0.75 | ALDH1A1 (0.51) | ALDH1A1TSHRFDPSAOX1TRIM24 | |
| SCHEMBL320559 | 0.75 | JUN (0.57) | ALDH1A1TSHRFDPSAOX1TRIM24 | |
| SCHEMBL31190039 | 0.75 | JUN (0.57) | ALDH1A1TSHRFDPSAOX1TRIM24 | |
| SCHEMBL8846494 | 0.75 | ALOX15 (0.44) | HTT | |
| SCHEMBL891572 | 0.74 | FGFR1 (0.65) | ALDH1A1TSHRFDPSAOX1TRIM24 | |
| SCHEMBL5784373 | 0.73 | ALDH1A1 (0.60) | ALDH1A1TSHRFDPSHPGDTDP1 | |
| SCHEMBL7195683 | 0.73 | ALDH1A1 (0.52) | ALDH1A1TSHRFDPSAOX1TRIM24 | |
| SCHEMBL7665789 | 0.72 | ALDH1A1 (0.67) | ALDH1A1TSHRFDPSAOX1TRIM24 | |
| SCHEMBL11010952 | 0.72 | ALDH1A1 (0.53) | ALDH1A1TSHRTRIM24HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664282-B1 | Biaryl phospholipase A2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0664282-A1 | Biaryl phospholipase A2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-26 | — | — | EP | disclosed |