SCHEMBL891572

SCHEMBL891572

CCC(=O)Oc1ccc(C=O)cc1OC

nearest known ligand 0.76

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.65
VCP P55072 1/20 0.65
ALDH1A1 P00352 8/20 0.64
TSHR P16473 1/20 0.64
FDPS P14324 1/20 0.59
KDM4E B2RXH2 1/20 0.58
MAPT P10636 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.56
AOX1 Q06278 1/20 0.54
TRIM24 O15164 1/20 0.54
HPGD P15428 1/20 0.54
ALDH5A1 P51649 1/20 0.54
ABAT P80404 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
TRIM33 Q9UPN9 1/20 0.54
TOP2A P11388 1/20 0.53
POLB P06746 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4090523 0.89 ALDH1A1 (0.66) ALDH1A1TSHRFDPSKDM4EMAPT
SCHEMBL891609 0.88 ALDH1A1 (0.60) FGFR1VCPALDH1A1TSHRFDPS
SCHEMBL4645057 0.88 ALDH1A1 (0.64) ALDH1A1TSHRFDPSKDM4EMAPT
SCHEMBL31756896 0.86 TOP2A (0.63) ALDH1A1TSHRFDPSKDM4EMAPT
SCHEMBL31096971 0.86 ALDH1A1 (0.62) ALDH1A1TSHRFDPSKDM4EMAPT
SCHEMBL4642389 0.86 TOP2A (0.71) ALDH1A1TSHRFDPSKDM4EMAPT
SCHEMBL27869198 0.86 ALDH1A1 (0.62) FGFR1ALDH1A1TSHRFDPSKDM4E
SCHEMBL4643932 0.86 ALDH1A1 (0.62) ALDH1A1TSHRFDPSKDM4EMAPT
SCHEMBL891219 0.85 TOP2A (0.66) FGFR1VCPALDH1A1TSHRFDPS
SCHEMBL10404703 0.85 KDM4E (0.51) FGFR1VCPALDH1A1TSHRFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2621462-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR The Procter and Gamble Company (US) 2013-08-07 EP claimed
CN-103140209-A Oral care compositions with improved flavor PROCTER & GAMBLE 2013-06-05 CN claimed
WO-2012044728-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR THE PROCTER & GAMBLE COMPANY (US) 2012-04-05 WO claimed
US-20120082628-A1 Oral Care Compositions With Improved Flavor THE PROCTER & GAMBLE COMPANY 2012-04-05 US claimed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
WO-2021071136-A2 NOVEL PRESERVATIVE, AND METHOD FOR PRODUCING SAME 동국대학교 산학협력단 2021-04-15 WO disclosed
CN-105814211-B Method for producing single cell oil from lignocellulosic material 耐思特公司 2020-11-06 CN disclosed
CN-111433577-A Temperature detection label and article management device using same 株式会社日立制作所 2020-07-17 CN disclosed
EP-2621462-B1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR PROCTER & GAMBLE (US) 2020-02-12 EP disclosed
US-9937115-B2 Oral care compositions with improved flavor THE PROCTER & GAMBLE COMPANY (US) 2018-04-10 US disclosed
CN-103140209-B Oral care composition with improved local flavor 宝洁公司 2017-10-13 CN disclosed
CN-101969791-B seasoning method GIVAUDAN SA 2013-10-30 CN disclosed
EP-2237683-A2 METHOD OF FLAVORING Givaudan SA (CH) 2010-10-13 EP disclosed
US-20100087524-A1 Flavour Improving Substances GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2010-04-08 US disclosed
EP-2124630-A1 FLAVOUR IMPROVING SUBSTANCES Givaudan Nederland Services B.V. (NL) 2009-12-02 EP disclosed
WO-2009092176-A2 METHOD OF FLAVORING GIVAUDAN SA (CH) 2009-07-30 WO disclosed
US-20090186138-A1 Method of Flavoring GIVAUDAN SA (CH) 2009-07-23 US disclosed
US-20090186138-A1 Method of Flavoring GIVAUDAN SA (CH) 2009-07-23 US disclosed
US-20090186138-A1 Method of Flavoring GIVAUDAN SA (CH) 2009-07-23 US disclosed
WO-2008105652-A1 FLAVOUR IMPROVING SUBSTANCES GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2008-09-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090186138-A1 Method of Flavoring TAS2R5, TAS2R50, TAS2R10 FGFR1 1509/4885VCP 3819/4885ALDH1A1 967/4885
US-20100087524-A1 Flavour Improving Substances SDHA, DLAT, LPO FGFR1 1461/4885VCP 2853/4885ALDH1A1 297/4885
US-20120082628-A1 Oral Care Compositions With Improved Flavor TRPA1, TAS2R40, TAS2R30 FGFR1 3190/4885VCP 3532/4885ALDH1A1 1558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.