SCHEMBL8846159

SCHEMBL8846159

O=C(CC(=O)C(=O)O)CC1C(F)C1c1ccc(Br)c(Br)c1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9567048 0.66 TRPM8 (0.33)
SCHEMBL9430217 0.64
SCHEMBL9257931 0.64
SCHEMBL9190928 0.61 AKR1C3 (0.33)
SCHEMBL9258443 0.59 RXRA (0.36)
SCHEMBL2165402 0.58 ALDH1A1 (0.50)
SCHEMBL16399374 0.54 ESR2 (0.37)
SCHEMBL18145957 0.53 SLC9A1 (0.38)
SCHEMBL18145953 0.53 SLC9A1 (0.38)
Acetic Acid SCHEMBL28090418 0.53 CA1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5605912-A INSECTICIDES, MITICIDES ROUSSEL UCLAF (FR) 1997-02-25 US disclosed
US-5380733-A Certain pyridyl-5-phenyl-1-cyclopropyl-dienamide pesticides ROUSSEL UCLAF (FR) 1995-01-10 US disclosed