Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648212 | 0.80 | GCGR (0.62) | GCGRALDH1A1L3MBTL1TRPM8GRM6 | |
| SCHEMBL15481445 | 0.77 | ALDH1A1 (0.47) | GCGRALDH1A1L3MBTL1TRPM8GRM6 | |
| SCHEMBL9271574 | 0.76 | PRKCZ (0.50) | GCGRALDH1A1L3MBTL1TRPM8GRM6 | |
| SCHEMBL3843460 | 0.75 | PRKCZ (0.52) | GCGRALDH1A1L3MBTL1TRPM8GRM6 | |
| SCHEMBL3206 | 0.74 | GCGR (0.47) | GCGRALDH1A1L3MBTL1TRPM8GRM6 | |
| SCHEMBL2648227 | 0.74 | GCGR (0.60) | GCGRALDH1A1L3MBTL1SLC10A2 | |
| SCHEMBL2647286 | 0.74 | GCGR (0.79) | GCGR | |
| SCHEMBL2211 | 0.74 | ALDH1A1 (0.47) | GCGRALDH1A1L3MBTL1TRPM8GRM6 | |
| SCHEMBL2662902 | 0.74 | GCGR (0.55) | GCGRALDH1A1L3MBTL1TRPM8GRM6 | |
| SCHEMBL3589 | 0.74 | ALDH1A1 (0.44) | GCGRALDH1A1L3MBTL1TRPM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641762-B1 | Process for preparation of 5-hydroxy-3-ketoester derivative and optically active substance thereof | UBE INDUSTRIES (JP) | 1997-05-28 | — | — | EP | disclosed |
| US-5457225-A | Process for preparation of 5-hydroxy-3-ketoester derivative and optically active substance thereof | UBE INDUSTRIES LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0641762-A1 | Process for preparation of 5-hydroxy-3-ketoester derivative and optically active substance thereof | UBE INDUSTRIES, LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |