Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | DVL1 | O14640 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26382364 | 0.91 | PPARD (0.83) | PPARDKDM4EHPGDMAPTPOLB | |
| SCHEMBL15870732 | 0.75 | KMT2A (0.73) | PPARDKDM4EHPGDMAPTKMT2A | |
| SCHEMBL8846503 | 0.75 | PPARD (0.60) | PPARDHPGDMAPTPOLBKMT2A | |
| SCHEMBL24323517 | 0.75 | PPARD (0.59) | PPARDKDM4EMAPTPOLBKMT2A | |
| SCHEMBL13458590 | 0.75 | KMT2A (0.67) | PPARDHPGDMAPTPOLBKMT2A | |
| SCHEMBL17164070 | 0.75 | POLB (0.66) | PPARDKDM4EHPGDPOLBKMT2A | |
| SCHEMBL16384637 | 0.74 | ALDH1A1 (0.63) | PPARDMAPTPOLBKMT2AMEN1 | |
| SCHEMBL24322995 | 0.74 | PPARD (0.58) | PPARDKDM4EMAPTPOLBKMT2A | |
| SCHEMBL17277318 | 0.73 | POLB (0.68) | PPARDHPGDPOLBKMT2AMEN1 | |
| SCHEMBL9192309 | 0.73 | ALOX15 (0.76) | PPARDKDM4EGAALTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11771702-B2 | Agonists of PPAR-δ | Goldblum, Amiram (IL) | 2023-10-03 | — | — | US | disclosed |
| US-11771702-B2 | Agonists of PPAR-δ | Goldblum, Amiram (IL) | 2023-10-03 | — | — | US | disclosed |
| US-20220023308-A1 | AGONISTS OF PPAR-delta | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2022-01-27 | — | — | US | disclosed |
| WO-2020110126-A1 | AGONISTS OF PPAR-δ | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2020-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11771702-B2 | Agonists of PPAR-δ | PPARD, PPARA, PPARG | PPARD 1/4885KDM4E 4373/4885HPGD 771/4885 |
| US-20220023308-A1 | AGONISTS OF PPAR-delta | PPARD, PPARG, PPARA | PPARD 1/4885KDM4E 4447/4885HPGD 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.