Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846600 | 0.85 | HPGD (0.68) | NPSR1HPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL9152872 | 0.83 | ALDH1A1 (0.66) | HSD17B10NPSR1MAPTHPGDLMNA | |
| SCHEMBL9152090 | 0.82 | PTGDR2 (0.51) | HSD17B10MAPTHPGDTSHRKMT2A | |
| SCHEMBL8846787 | 0.81 | USP2 (0.62) | NPSR1MAPTHPGDTSHRLMNA | |
| SCHEMBL7391021 | 0.78 | ADORA3 (0.53) | HSD17B10MAPTHPGDTSHRLMNA | |
| SCHEMBL7398072 | 0.77 | HSD17B10 (0.80) | HSD17B10NPSR1HPGDTSHRLMNA | |
| SCHEMBL7543877 | 0.76 | MAPT (0.49) | MAPTHPGDTSHRLMNAKMT2A | |
| SCHEMBL8846503 | 0.75 | PPARD (0.60) | HSD17B10MAPTHPGDKMT2AGAA | |
| SCHEMBL8846760 | 0.74 | MEN1 (0.61) | MAPTLMNAKMT2AGAAPKM | |
| SCHEMBL20463424 | 0.74 | MTNR1A (0.72) | HSD17B10HPGDLMNAMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641768-B1 | NITROXYALKYLAMIDE DERIVATIVE | SANKYO CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5580893-A | TREATMENT AND PREVENTION OF ANGINA PECTORIS; SIDE-EFFECT REDUCTION; VASODILATION | SANKYO COMPANY, LIMITED (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0641768-A1 | NITROXYALKYLAMIDE DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |