Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848788 | 0.84 | MEN1 (0.64) | LMNANPSR1LTA4HNPC1TSHR | |
| SCHEMBL8848575 | 0.84 | MAOB (0.54) | LMNALTA4HNPC1TSHRRAB9A | |
| SCHEMBL8848549 | 0.82 | TP53 (0.52) | LMNANPC1TSHRRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8848858 | 0.81 | LTA4H (0.62) | LMNALTA4HNPC1TSHRRAB9A | |
| SCHEMBL8848722 | 0.81 | RAB9A (0.65) | LMNALTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8848545 | 0.81 | RAB9A (0.52) | LMNANPC1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL8848606 | 0.81 | SMN1; SMN2 (0.51) | LMNANPSR1NPC1TSHRRAB9A | |
| SCHEMBL8848588 | 0.81 | LTA4H (0.48) | LMNALTA4HNPC1TSHRRAB9A | |
| Hydrochloric Acid SCHEMBL8848620 | 0.80 | LMNA (0.46) | LMNALTA4HNPC1TSHRRAB9A | |
| SCHEMBL8848732 | 0.80 | RAB9A (0.51) | LMNANPC1TSHRRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602161-A | ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0676396-A1 | Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |