SCHEMBL8848846

SCHEMBL8848846

Cc1c(Cl)cccc1OC#N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
MRGPRX4 Q96LA9 1/20 0.38
AR P10275 2/20 0.36
EPAS1 Q99814 1/20 0.35
KMT2A Q03164 1/20 0.33
HSD11B1 P28845 3/20 0.33
NR1I2 O75469 1/20 0.33
PSMB8 P28062 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.33
MAPT P10636 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
LMNA P02545 2/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
ADRB2 P07550 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18541925 0.85 MAPT (0.39) ALDH1A1ARMAPTLMNAKDM4E
SCHEMBL29489121 0.79 MAPT (0.46) ALDH1A1ARKMT2AMAPTLMNA
SCHEMBL9854216 0.79 MAPT (0.46) ALDH1A1ARKMT2AMAPTLMNA
SCHEMBL11851873 0.79 LMNA (0.42) ALDH1A1ARKMT2AMAPTSLC6A2
SCHEMBL18469427 0.78 CA1 (0.42) ALDH1A1ARMAPTLMNAKDM4E
SCHEMBL27904645 0.76 NPC1 (0.32) AR
SCHEMBL18427386 0.76 LMNA (0.36) ALDH1A1LMNA
SCHEMBL22172091 0.76 TSHR (0.43) ALDH1A1ARGAASMN1; SMN2POLB
SCHEMBL8760084 0.76 MRGPRX4 (0.44) ALDH1A1MRGPRX4KMT2AMAPTHTT
SCHEMBL16707418 0.75 ALDH1A1 (0.31) ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3438146-B1 CYANIC ACID ESTER COMPOUND AND METHOD FOR PRODUCING SAME, RESIN COMPOSITION, CURED ARTICLE, PREPREG, SEALING MATERIAL, FIBER-REINFORCED COMPOSITE MATERIAL, ADHESIVE AGENT, METAL FOIL-CLAD LAMINATE PLATE, RESIN SHEET, AND PRINTED WIRING BOARD MITSUBISHI GAS CHEMICAL CO (JP) 2026-04-08 EP disclosed
US-12486371-B2 Thermally curable resin composition, cured object, resin sheet, prepreg, metal-clad laminate, multilayered printed wiring board, sealing material, fiber-reinforced composite material, adhesive, and semiconductor device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-12-02 US disclosed
EP-3805293-B1 RESIN COMPOSITION, PREPREG, METAL FOIL-CLAD LAMINATE, RESIN SHEET, AND PRINTED WIRING BOARD MITSUBISHI GAS CHEMICAL CO (JP) 2025-09-17 EP disclosed
US-12312323-B2 Compound, method for producing same, resin composition, resin sheet, multilayer printed wiring board, and semiconductor device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-05-27 US disclosed
CN-119866352-A Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 日本化药株式会社 2025-04-22 CN disclosed
CN-115003716-B Resin composition, resin sheet, prepreg, and printed wiring board 三菱瓦斯化学株式会社 2025-04-11 CN disclosed
US-20250109222-A1 CYCLIC ORGANOSILOXANE CONTAINING IMIDE BOND AND POLYMERIZABLE UNSATURATED BOND, AND CURABLE RESIN COMPOSITION COMPRISING SAID CYCLIC ORGANOSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-03 US disclosed
CN-117529509-B Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 三菱瓦斯化学株式会社 2025-01-10 CN disclosed
CN-117355545-B Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 三菱瓦斯化学株式会社 2024-10-18 CN disclosed
EP-4438655-A1 CYCLIC ORGANOSILOXANE CONTAINING IMIDE BOND AND POLYMERIZABLE UNSATURATED BOND, AND CURABLE RESIN COMPOSITION COMPRISING SAID CYCLIC ORGANOSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-10-02 EP disclosed
CN-105308084-A Cyanate ester compound, curable resin composition containing said compound, and cured product of said composition MITSUBISHI GAS CHEMICAL CO 2016-02-03 CN disclosed
CN-105308118-A Resin composition, prepreg, resin sheet, and metal foil-clad laminate MITSUBISHI GAS CHEMICAL CO 2016-02-03 CN disclosed
US-20150299110-A1 METHOD FOR PRODUCING CYANOGEN-HALIDE, CYANATE ESTER COMPOUND AND METHOD FOR PRODUCING THE SAME, AND RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2015-10-22 US disclosed
EP-2913302-A1 CYANOGEN-HALIDE PRODUCTION METHOD, CYANATE ESTER COMPOUND AND PRODUCTION METHOD THEREFOR, AND RESIN COMPOSITION Mitsubishi Gas Chemical Company, Inc. (JP) 2015-09-02 EP disclosed
CN-104755422-A Method for producing cyanogen halide, cyanate ester compound and method for producing same, and resin composition MITSUBISHI GAS CHEMICAL CO 2015-07-01 CN disclosed
US-5623006-A HAVING GAP FILLED WITH CURED POLYCYANURATE BINDER INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-04-22 US disclosed
US-5536765-A CYANATE TRIMERIZATION INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1996-07-16 US disclosed
US-5468790-A Useful in forming interconnection structures for integrated semiconductor devices INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1995-11-21 US disclosed
EP-0604823-A1 Triazine polymer and use thereof International Business Machines Corporation (US) 1994-07-06 EP disclosed
US-3994949-A REACTION OF PHENOLATE WITH CYANOGEN HALIDE, TERT-AMINE CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299110-A1 METHOD FOR PRODUCING CYANOGEN-HALIDE, CYANATE ESTER COMPOUND AND METHOD FOR PRODUCING THE SAME, AND RESIN COMPOSITION MB, CBR3, CRYAA ALDH1A1 4196/4885MRGPRX4 793/4885AR 3636/4885
US-20250109222-A1 CYCLIC ORGANOSILOXANE CONTAINING IMIDE BOND AND POLYMERIZABLE UNSATURATED BOND, AND CURABLE RESIN COMPOSITION COMPRISING SAID CYCLIC ORGANOSILOXANE ZYX, MUS81, H1-0 ALDH1A1 3113/4885MRGPRX4 1949/4885AR 3186/4885
US-12312323-B2 Compound, method for producing same, resin composition, resin sheet, multilayer printed wiring board, and semiconductor device ASH2L, RER1, SEM1 ALDH1A1 659/4885MRGPRX4 2180/4885AR 2661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.