Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872303 | 0.76 | CA4 (0.36) | LMNAKMT2AHPGDALOX15TSHR | |
| SCHEMBL1832601 | 0.64 | LMNA (0.50) | LMNACYP2A6SLC6A4ADRB2MEN1 | |
| SCHEMBL29776864 | 0.64 | LMNA (0.50) | LMNACYP2A6SLC6A4ADRB2MEN1 | |
| SCHEMBL18553059 | 0.64 | ADRB2 (0.48) | LMNACYP2A6SLC6A4AOC3ADRB2 | |
| SCHEMBL791590 | 0.64 | IDO1 (0.56) | LMNACYP2A6SLC6A4AOC3ADRB2 | |
| SCHEMBL654510 | 0.64 | ADRB2 (0.48) | LMNACYP2A6SLC6A4AOC3ADRB2 | |
| SCHEMBL8459846 | 0.63 | LMNA (0.57) | LMNACYP2A6ADRB2MEN1KMT2A | |
| SCHEMBL3043487 | 0.62 | LMNA (0.47) | LMNACYP2A6SLC6A4ADRB2MEN1 | |
| SCHEMBL15854056 | 0.62 | ADRB2 (0.52) | LMNACYP2A6SLC6A4AOC3ADRB2 | |
| SCHEMBL11403506 | 0.62 | AOC3 (0.50) | LMNACYP2A6SLC6A4AOC3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671417-B1 | Components and catalysts for the copolymerisation of olefins | MONTELL NORTH AMERICA INC (US) | 1997-05-02 | — | — | EP | disclosed |
| EP-0437263-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1995-11-08 | — | — | EP | disclosed |
| EP-0671417-A2 | Components and catalysts for the copolymerisation of olefins | MONTELL NORTH AMERICA INC. (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5106807-A | Coordination catalysts comprising a dihydrocarbylethermethyl silane, a titanium halide and a magnesium halide support; stereospecific | HIMONT INCORPORATED (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0437263-A1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1991-07-17 | — | — | EP | disclosed |