SCHEMBL1832601

SCHEMBL1832601

C[SiH](C)c1ccc(Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
CYP2A6 P11509 1/20 0.50
ALDH1A1 P00352 2/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
IDO1 P14902 2/20 0.38
TSHR P16473 2/20 0.38
ALOX15 P16050 2/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ADRB2 P07550 1/20 0.36
CYP1A2 P05177 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HSD17B10 Q99714 2/20 0.33
CES2 O00748 2/20 0.33
CES1 P23141 2/20 0.33
SRD5A2 P31213 1/20 0.33
ENPP2 Q13822 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148576 0.83
SCHEMBL2438805 0.83
SCHEMBL29776864 0.81 LMNA (0.50) LMNACYP2A6ALDH1A1CYP3A4MAPK1
SCHEMBL3043487 0.79 LMNA (0.47) LMNACYP2A6ALDH1A1CYP3A4MAPK1
SCHEMBL8459846 0.73 LMNA (0.57) LMNACYP2A6ALDH1A1CYP3A4MAPK1
SCHEMBL2579397 0.73 ALDH1A1 (0.32) ALDH1A1CYP3A4
SCHEMBL5246070 0.71 LMNA (0.53) LMNACYP2A6ALDH1A1CYP3A4MAPK1
SCHEMBL476102 0.71 ACHE (0.53) LMNACYP2A6ALDH1A1IDO1TSHR
SCHEMBL13699095 0.71 TYR (0.42) LMNAALDH1A1MAPK1IDO1KDM4E
1,4-Dichlorobenzene SCHEMBL5191 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115926587-A Anti-corrosion wear-resistant coating and preparation method thereof 辽宁石油化工大学 2023-04-07 CN claimed
CN-120040492-A Method for synthesizing silanol by catalyzing and oxidizing silane with polyacid 辽宁科技大学 2025-05-27 CN disclosed
CN-119119106-A Method for preparing silanol by selective oxidation of hydrosilane under catalysis of nano porous palladium copper 大连理工大学 2024-12-13 CN disclosed
CN-118027090-A Method for generating silanol by oxidizing silane 吉林大学 2024-05-14 CN disclosed
CN-115926587-A Anti-corrosion wear-resistant coating and preparation method thereof 辽宁石油化工大学 2023-04-07 CN disclosed
CN-115926587-A Anti-corrosion wear-resistant coating and preparation method thereof 辽宁石油化工大学 2023-04-07 CN disclosed
US-11505460-B2 Method for producing silanol compound and hydrogen OSAKA UNIVERISTY (JP) 2022-11-22 US disclosed
CN-108349897-B Trisubstituted silylphenoxyheterocycles and analogs 拜耳作物科学股份公司 2022-03-04 CN disclosed
CN-112961179-A Preparation method of borosiloxane compound 云南民族大学 2021-06-15 CN disclosed
US-10927355-B2 Method for producing an organosilicon product CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2021-02-23 US disclosed
US-5677291-A Method of lowering serum cholesterol levels with 2,6-di-alkyl-4-silyl-phenols HOECHST MARION ROUSSEL, INC. (US) 1997-10-14 US disclosed
EP-0466183-B1 Cyclosiloxanes with mesogenic side groups CONSORTIUM ELEKTROCHEM IND (DE) 1995-09-20 EP disclosed
US-5342984-A Triorganomonohalogenosilane SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-08-30 US disclosed
US-5304667-A Cyclosiloxanes containing mesogenic side groups CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1994-04-19 US disclosed
EP-0577139-A1 Method for preparing triorganomonohalogenosilane Shin-Etsu Chemical Co., Ltd. (JP) 1994-01-05 EP disclosed
US-5221759-A CYCLOSILOXANES CONTAINING MESOGENIC SIDE GROUPS CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1993-06-22 US disclosed
EP-0466183-A1 Cyclosiloxanes with mesogenic side groups Consortium für elektrochemische Industrie GmbH (DE) 1992-01-15 EP disclosed
EP-0304720-B1 DIMETHYLSILYL SUBSTITUTED BENZOYLCHLORIDES AND PROCESS FOR THEIR PREPARATION Consortium für elektrochemische Industrie GmbH (DE) 1991-06-26 EP disclosed
US-4914221-A Dimethylsilyl-substituted benzoyl chlorides and a process for preparing the same CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1990-04-03 US disclosed
EP-0304720-A1 Dimethylsilyl substituted benzoylchlorides and process for their preparation Consortium für elektrochemische Industrie GmbH (DE) 1989-03-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10927355-B2 Method for producing an organosilicon product HMOX2, HMOX1, HMBS LMNA 2819/4885CYP2A6 582/4885ALDH1A1 4117/4885
US-11505460-B2 Method for producing silanol compound and hydrogen HVCN1, SOST, HAO2 LMNA 4002/4885CYP2A6 3467/4885ALDH1A1 1051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.