Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18726525 | 0.80 | THRB (0.38) | CA4THRBCA12CA1CA2 | |
| SCHEMBL5872426 | 0.78 | CA4 (0.35) | CA4THRBCA12CA1CA2 | |
| SCHEMBL8848922 | 0.78 | ACHE (0.39) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL8849347 | 0.76 | LMNA (0.36) | KMT2ALMNAHPGDALOX15HIF1A | |
| SCHEMBL820791 | 0.76 | CA4 (0.39) | CA4THRBLTA4H | |
| SCHEMBL584271 | 0.72 | ALDH1A1 (0.30) | CA4THRBALDH1A1TSHR | |
| SCHEMBL1548462 | 0.72 | TAAR1 (0.33) | CA4THRB | |
| SCHEMBL1325645 | 0.70 | TDP1 (0.36) | THRBKDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL6512618 | 0.70 | HPGD (0.32) | CYP3A4HPGD | |
| SCHEMBL10356057 | 0.70 | L3MBTL1 (0.31) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671417-B1 | Components and catalysts for the copolymerisation of olefins | MONTELL NORTH AMERICA INC (US) | 1997-05-02 | — | — | EP | claimed |
| EP-0671417-A2 | Components and catalysts for the copolymerisation of olefins | MONTELL NORTH AMERICA INC. (US) | 1995-09-13 | — | — | EP | claimed |
| US-5106807-A | Coordination catalysts comprising a dihydrocarbylethermethyl silane, a titanium halide and a magnesium halide support; stereospecific | HIMONT INCORPORATED (US) | 1992-04-21 | — | — | US | claimed |
| EP-0437263-A1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1991-07-17 | — | — | EP | claimed |
| US-7022796-B2 | Using coordination catalysts | FINA TECHNOLOGY, INC. (US) | 2006-04-04 | — | — | US | disclosed |
| US-20040116629-A1 | Production of ultra high melt flow polypropylene resins | FINA TECHNOLOGY INC. | 2004-06-17 | — | — | US | disclosed |
| US-6657025-B2 | Using coordination polymerization catalyst | FINA TECHNOLOGY, INC. | 2003-12-02 | — | — | US | disclosed |
| US-20020161139-A1 | Production of ultra high melt flow polypropylene resins | FINA TECHNOLOGY, INC. | 2002-10-31 | — | — | US | disclosed |
| EP-1223181-A2 | Production of ultra high melt flow polypropylene resins | FINA TECHNOLOGY, INC. (US) | 2002-07-17 | — | — | EP | disclosed |
| EP-0671417-B1 | Components and catalysts for the copolymerisation of olefins | MONTELL NORTH AMERICA INC (US) | 1997-05-02 | — | — | EP | disclosed |
| EP-0437263-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1995-11-08 | — | — | EP | disclosed |
| EP-0671417-A2 | Components and catalysts for the copolymerisation of olefins | MONTELL NORTH AMERICA INC. (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5106807-A | Coordination catalysts comprising a dihydrocarbylethermethyl silane, a titanium halide and a magnesium halide support; stereospecific | HIMONT INCORPORATED (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0437263-A1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1991-07-17 | — | — | EP | disclosed |