Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.40 |
| ▸ | DUT | P33316 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850313 | 0.89 | TBXA2R (0.40) | FABP4FABP5CYP2D6PTGDR2KMT2A | |
| SCHEMBL8851069 | 0.89 | KDM4E (0.36) | FABP4FABP5DUTKDM4ETP53 | |
| SCHEMBL8850682 | 0.87 | CYP1A2 (0.40) | FABP4FABP5PTGDR2MEN1KMT2A | |
| SCHEMBL8850540 | 0.85 | TNF (0.52) | DUTKDM4ETP53CYP2D6HTT | |
| SCHEMBL6198182 | 0.84 | KMT2A (0.42) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL6195293 | 0.84 | KDM4E (0.41) | DUTKDM4ETP53CYP2D6HTT | |
| SCHEMBL27481986 | 0.83 | KMT2A (0.41) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL8849907 | 0.80 | HTT (0.46) | DUTHTTSMN1; SMN2PTGER4PTGER2 | |
| SCHEMBL6197640 | 0.80 | KDM4E (0.46) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL6196471 | 0.80 | KDM4E (0.41) | DUTKDM4ETP53CYP2D6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688815-A | COMPOUNDS FOR REMOVAL OF EXCESS IRON IN MAMMALS | CIBA GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| CN-1151399-A | Novel hydroxylpyridinones | CIBA GEIGY AG (CH) | 1997-06-11 | — | — | CN | disclosed |