Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11663021 | 0.82 | POLB (0.51) | POLBHIF1ACYP2D6ADRB2ADRB1 | |
| SCHEMBL9652459 | 0.81 | ALDH1A1 (0.35) | LMNACYP3A4MAPT | |
| SCHEMBL8850124 | 0.77 | CA1 (0.36) | — | |
| SCHEMBL8849968 | 0.77 | LTA4H (0.40) | CYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21792721 | 0.74 | POLB (0.54) | POLBHIF1ACYP2D6ADRB2ADRB1 | |
| SCHEMBL13952042 | 0.72 | POLB (0.78) | POLBHIF1ACYP2D6ADRB2ADRB1 | |
| SCHEMBL10760842 | 0.72 | POLB (0.78) | POLBHIF1ACYP2D6ADRB2ADRB1 | |
| SCHEMBL1637760 | 0.72 | S100B (0.47) | HIF1ALMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL166337 | 0.70 | LMNA (0.64) | POLBHIF1ACYP2D6ADRB2ADRB1 | |
| SCHEMBL27685093 | 0.70 | TSHR (0.61) | LMNACYP2C19MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679800-A | DISPERSE DYES AND INTERMEDIATES FOR DISPERSE DYES | CLARIANT FINANCE (BVI) LIMITED (VG) | 1997-10-21 | — | — | US | disclosed |
| US-5132411-A | Blue shades | SANDOZ LTD. (CH) | 1992-07-21 | — | — | US | disclosed |