SCHEMBL8850427

SCHEMBL8850427

C=C(C(=O)O)C(C)C(=C(C)C(=O)O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
LMNA P02545 3/20 0.53
NPSR1 Q6W5P4 3/20 0.53
XBP1 P17861 1/20 0.53
ATM Q13315 1/20 0.53
ALDH1A1 P00352 6/20 0.41
HPGD P15428 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CES1 P23141 3/20 0.38
CES2 O00748 2/20 0.38
CYP3A4 P08684 2/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
PAX8 Q06710 1/20 0.36
KDM4E B2RXH2 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6472934 0.84 MAPT (0.44) MAPTSMN1; SMN2LMNANPSR1XBP1
SCHEMBL6472265 0.80 CES1 (0.45) MAPTSMN1; SMN2LMNANPSR1XBP1
SCHEMBL16697813 0.77 CES1 (0.42) MAPTSMN1; SMN2LMNANPSR1XBP1
SCHEMBL10777198 0.69 SMN1; SMN2 (0.49) MAPTSMN1; SMN2LMNANPSR1XBP1
SCHEMBL1173261 0.68 PGR (0.43) MAPTSMN1; SMN2LMNANPSR1XBP1
Methacrylic Acid SCHEMBL5955924 0.68 CES1 (0.45) MAPTSMN1; SMN2LMNANPSR1XBP1
SCHEMBL1232452 0.68 CES1 (0.54) MAPTSMN1; SMN2LMNAALDH1A1HPGD
SCHEMBL367456 0.68 CES1 (0.54) MAPTSMN1; SMN2LMNAALDH1A1HPGD
SCHEMBL367453 0.68 CES1 (0.54) MAPTSMN1; SMN2LMNAALDH1A1HPGD
SCHEMBL2915534 0.67 LMNA (0.46) MAPTSMN1; SMN2LMNANPSR1XBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9856373-B2 (Meth)acrylate-based resin composition having excellent impact resistance and transparency LG CHEM, LTD. (KR) 2018-01-02 US disclosed
US-20160115309-A1 (METH)ACRYLATE-BASED RESIN COMPOSITION HAVING EXCELLENT IMPACT RESISTANCE AND TRANSPARENCY LG CHEM, LTD. (KR) 2016-04-28 US disclosed
EP-0477726-B1 Ternary mixtures of polymers ROEHM GMBH (DE) 1997-03-12 EP disclosed
EP-0477726-A1 Ternary mixtures of polymers RÖHM GMBH (DE) 1992-04-01 EP disclosed