Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8852843 | 1.00 | PPARG (0.46) | PPARGPPARALTA4HLAP3MMP12 | |
| SCHEMBL27492803 | 0.83 | YAP1 (0.45) | LTA4HLAP3ITGB3ITGA2BYAP1 | |
| SCHEMBL8460143 | 0.76 | REN (0.59) | YAP1 | |
| SCHEMBL8460817 | 0.76 | REN (0.59) | YAP1 | |
| SCHEMBL4883264 | 0.74 | EPHX2 (0.64) | LTA4HKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL28064096 | 0.74 | PPARG (0.57) | PPARGPPARALTA4HLAP3PPARD | |
| SCHEMBL28224291 | 0.73 | FFAR1 (0.64) | PPARGPPARALTA4HLAP3MMP12 | |
| SCHEMBL28860722 | 0.73 | FFAR1 (0.64) | PPARGPPARALTA4HLAP3MMP12 | |
| SCHEMBL8892865 | 0.73 | LTA4H (0.64) | PPARGPPARALTA4HLAP3PPARD | |
| SCHEMBL8892873 | 0.73 | LTA4H (0.64) | PPARGPPARALTA4HLAP3PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663200-A | CARBAMOYL PEPTIDE DERIVATIVES AS VIRICIDES | CIBA-GEIGY CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |