SCHEMBL8854366

SCHEMBL8854366

CC(=O)O[Si]1(OC(C)=O)CCCC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22632354 0.97 HSD17B10 (0.32) ALDH1A1HSD17B10TDP1TSHR
SCHEMBL9181709 0.94 ALDH1A1 (0.33) ALDH1A1HSD17B10TDP1TSHR
SCHEMBL20769862 0.87 ALDH1A1 (0.35) ALDH1A1
SCHEMBL20769888 0.85 ALDH1A1 (0.33) ALDH1A1
SCHEMBL20769869 0.84 ALDH1A1 (0.37) ALDH1A1HSD17B10TSHR
SCHEMBL20769858 0.82 ALDH1A1 (0.35) ALDH1A1
SCHEMBL20769887 0.79 ALDH1A1 (0.37) ALDH1A1HSD17B10TSHR
SCHEMBL4456584 0.77 ALDH1A1 (0.37) ALDH1A1HSD17B10TDP1TSHR
SCHEMBL20942803 0.76 HSD17B10 (0.32) ALDH1A1HSD17B10TDP1TSHR
SCHEMBL20942791 0.74 HSD17B10 (0.31) ALDH1A1HSD17B10TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240182499-A1 ALKOXYSILACYCLIC OR ACYLOXYSILACYCLIC COMPOUNDS AND METHODS FOR DEPOSITING FILMS USING SAME VERSUM MAT US LLC (US) 2024-06-06 US claimed
US-20220044928-A1 SILICON COMPOUNDS AND METHODS FOR DEPOSITING FILMS USING SAME VERSUM MATERIALS US, LLC (US) 2022-02-10 US claimed
US-11158498-B2 Silicon compounds and methods for depositing films using same VERSUM MATERIALS US, LLC (US) 2021-10-26 US claimed
US-20200354386-A1 ALKOXYSILACYCLIC OR ACYLOXYSILACYCLIC COMPOUNDS AND METHODS FOR DEPOSITING FILMS USING SAME VERSUM MATERIALS US, LLC 2020-11-12 US claimed
CN-111051568-A Alkoxy silicon heterocyclic or acyloxy silicon heterocyclic compound and method for depositing film using the same 弗萨姆材料美国有限责任公司 2020-04-21 CN claimed
US-20240182499-A1 ALKOXYSILACYCLIC OR ACYLOXYSILACYCLIC COMPOUNDS AND METHODS FOR DEPOSITING FILMS USING SAME VERSUM MAT US LLC (US) 2024-06-06 US disclosed
US-11884689-B2 Alkoxysilacyclic or acyloxysilacyclic compounds and methods for depositing films using same VERSUM MATERIALS US, LLC 2024-01-30 US disclosed
US-20220044928-A1 SILICON COMPOUNDS AND METHODS FOR DEPOSITING FILMS USING SAME VERSUM MATERIALS US, LLC (US) 2022-02-10 US disclosed
US-11158498-B2 Silicon compounds and methods for depositing films using same VERSUM MATERIALS US, LLC (US) 2021-10-26 US disclosed
US-20200354386-A1 ALKOXYSILACYCLIC OR ACYLOXYSILACYCLIC COMPOUNDS AND METHODS FOR DEPOSITING FILMS USING SAME VERSUM MATERIALS US, LLC 2020-11-12 US disclosed
CN-111051568-A Alkoxy silicon heterocyclic or acyloxy silicon heterocyclic compound and method for depositing film using the same 弗萨姆材料美国有限责任公司 2020-04-21 CN disclosed
US-5610259-A COMPRISING DIFUNCTIONAL SILACYCLOALKANES AND CROSSLINKER; CAULKING, SEALANTS GENERAL ELECTRIC COMPANY (US) 1997-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11158498-B2 Silicon compounds and methods for depositing films using same TET2, SMS, TET1 ALDH1A1 1111/4885HSD17B10 2491/4885TDP1 3241/4885
US-11884689-B2 Alkoxysilacyclic or acyloxysilacyclic compounds and methods for depositing films using same KCNC1, KCNH2, PORCN ALDH1A1 3870/4885HSD17B10 1308/4885TDP1 4387/4885
US-20240182499-A1 ALKOXYSILACYCLIC OR ACYLOXYSILACYCLIC COMPOUNDS AND METHODS FOR DEPOSITING FILMS USING SAME KCNC1, KCNH2, PORCN ALDH1A1 3870/4885HSD17B10 1308/4885TDP1 4387/4885
US-20220044928-A1 SILICON COMPOUNDS AND METHODS FOR DEPOSITING FILMS USING SAME TET2, SMS, TET1 ALDH1A1 1111/4885HSD17B10 2491/4885TDP1 3241/4885
US-20200354386-A1 ALKOXYSILACYCLIC OR ACYLOXYSILACYCLIC COMPOUNDS AND METHODS FOR DEPOSITING FILMS USING SAME KCNC1, KCNH2, PORCN ALDH1A1 3870/4885HSD17B10 1308/4885TDP1 4387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.