SCHEMBL8854545

SCHEMBL8854545

O=[PH](O)OCOS(=O)(=O)c1ccccc1Cl

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
F2 P00734 9/20 0.37
CTRC Q99895 3/20 0.36
F10 P00742 2/20 0.35
HSD11B1 P28845 2/20 0.35
POLB P06746 1/20 0.35
FLT1 P17948 1/20 0.35
FLT4 P35916 1/20 0.35
KDR P35968 1/20 0.35
ALDH1A1 P00352 2/20 0.34
PRSS2 P07478 2/20 0.34
HTT P42858 1/20 0.33
PGR P06401 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27468777 0.87 F2 (0.36) F2CTRCF10HSD11B1ALDH1A1
SCHEMBL8854423 0.83 KMT2A (0.33) POLBKMT2A
SCHEMBL8854645 0.82 ALDH1A1 (0.40) ALDH1A1
SCHEMBL8734595 0.81 F2 (0.38) F2CTRCF10HSD11B1ALDH1A1
Butane SCHEMBL8911066 0.78 KMT2A (0.38) POLBALDH1A1HTTKMT2A
SCHEMBL8854445 0.78 HPGD (0.32) ALDH1A1HTTKMT2A
SCHEMBL8854529 0.78 MEN1 (0.41) F2HSD11B1ALDH1A1KMT2A
SCHEMBL28684540 0.77 PARL (0.40) POLBALDH1A1KMT2A
SCHEMBL8854564 0.77 SLC40A1 (0.34) ALDH1A1HTTKMT2A
SCHEMBL8854638 0.76 ALOX15 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1173282-A Herbicidal method utilizing phosphosulfonate herbicides and oxime ether safeners ROHM & HAAS (US) 1998-02-18 CN claimed
US-5693590-A PLANT GROWTH REGULATOR ROHM AND HAAS COMPANY (US) 1997-12-02 US claimed
CN-1133120-A Combination containing phosphine sulfonate ester herbicide and dichloro acetamide safety agent ROHM & HAAS (US) 1996-10-16 CN claimed