Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699275 | 0.79 | DRD2 (0.33) | CA2 | |
| SCHEMBL19054489 | 0.76 | HTR7 (0.38) | KMT2ATDP1 | |
| SCHEMBL875341 | 0.76 | DRD2 (0.45) | — | |
| SCHEMBL9392163 | 0.76 | DRD2 (0.45) | — | |
| SCHEMBL30601522 | 0.76 | DRD2 (0.45) | — | |
| SCHEMBL23652957 | 0.76 | AADAT (0.37) | CA2 | |
| Hydrochloric Acid SCHEMBL21810859 | 0.75 | HTR2A (0.34) | — | |
| SCHEMBL6681925 | 0.75 | ALDH1A1 (0.44) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL5761600 | 0.74 | PARP1 (0.43) | — | |
| SCHEMBL13808984 | 0.72 | PTPRF (0.39) | MEN1LMNATHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656657-A | Chroman derivatives | ASTRA AKTIEBOLAG (SE) | 1997-08-12 | — | — | US | disclosed |