SCHEMBL88571

SCHEMBL88571

C=CCN(c1cc2ccccc2[nH]1)[C@@H](C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.40
HPGD P15428 2/20 0.40
ALDH1A1 P00352 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALOX5 P09917 1/20 0.40
TSHR P16473 4/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HSD17B10 Q99714 2/20 0.39
MAPT P10636 1/20 0.39
DAO P14920 1/20 0.39
SRD5A2 P31213 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMPD2 O60906 1/20 0.38
IDO1 P14902 1/20 0.37
FLT3 P36888 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28663705 0.78 KDM4E (0.47) KDM4EHPGDALDH1A1SMN1; SMN2ALOX5
SCHEMBL10589998 0.75 CYP2C19 (0.41) KDM4EALDH1A1SMN1; SMN2TSHRLMNA
SCHEMBL3665626 0.75 KDM4E (0.44) KDM4EHPGDALDH1A1SMN1; SMN2ALOX5
SCHEMBL19067175 0.74 KDM4E (0.46) KDM4EHPGDALDH1A1SMN1; SMN2ALOX5
SCHEMBL3393557 0.73 LOXL2 (0.41) KDM4EHPGDALDH1A1ALOX5LMNA
SCHEMBL3103110 0.69 KDM4E (0.43) KDM4EHPGDALOX5TSHRLMNA
1,2-Dichlorobenzene SCHEMBL28816513 0.69 TP53 (0.38) KDM4EHPGDALDH1A1SMN1; SMN2TSHR
SCHEMBL25305793 0.68 GSTO1 (0.46) KDM4EHPGDALDH1A1SMN1; SMN2LMNA
SCHEMBL12076389 0.67 CRHR1 (0.42) KDM4EHPGDALDH1A1SMN1; SMN2LMNA
SCHEMBL7321937 0.67 MEN1 (0.49) KDM4EHPGDALDH1A1SMN1; SMN2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1376 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3334759-B1 LACTOFERRIN FRAGMENT FOR THE USE AS ANTIBACTERIAL AND ANTIVIRAL AGENT FARMAGENS HEALTH CARE SRL (IT) 2019-09-04 EP claimed
EP-3334759-A1 LACTOFERRIN FRAGMENT FOR THE USE AS ANTIBACTERIAL AND ANTIVIRAL AGENT Farmagens Health Care Srl (IT) 2018-06-20 EP claimed
WO-2017025846-A1 LACTOFERRIN FRAGMENT FOR THE USE AS ANTIBACTERIAL AND ANTIVIRAL AGENT FARMAGENS HEALTH CARE SRL (IT) 2017-02-16 WO claimed
US-20030143664-A1 Products of manufacture and processes for peptide synthesis DIVERSA CORPORATION (US) 2003-07-31 US claimed
WO-2003048189-A2 PRODUCTS OF MANUFACTURE AND PROCESSES FOR PEPTIDE SYNTHESIS DIVERSA CORPORATION (US) 2003-06-12 WO claimed
EP-4398924-A1 TRANSMEMBRANE PEPTIDIC ANTAGONISTS OF PLEXIN-A1 AND THEIR THERAPEUTIC USES Université de Strasbourg (FR) 2024-07-17 EP disclosed
US-12023316-B2 FAP-activated therapeutic agents, and uses related thereto BACH BIOSCIENCES, LLC (US) 2024-07-02 US disclosed
EP-4389757-A2 METHODS FOR PURIFYING ANTIBODIES GlaxoSmithKline Intellectual Property Development Limited (GB) 2024-06-26 EP disclosed
WO-2024129720-A2 T CELL RECEPTOR CONSTRUCTS AND USES THEREOF BIONTECH US INC. (US) 2024-06-20 WO disclosed
WO-2024103178-A1 ANISOMYCIN ANALOGS AND USES THEREOF Université de Montréal (CA) 2024-05-23 WO disclosed
EP-4371996-A2 METHODS FOR PURIFYING ANTIBODIES GlaxoSmithKline Intellectual Property Development Limited (GB) 2024-05-22 EP disclosed
EP-3510042-B1 METHODS FOR PURIFYING ANTIBODIES GLAXOSMITHKLINE IP DEV LTD (GB) 2024-05-22 EP disclosed
US-5591716-A Beneficial wound healing applications of calreticulin and other hyaluronan-associated proteins NEW YORK UNIVERSITY (US) 1997-01-07 US disclosed
WO-1997000081-A1 A METHOD FOR INHIBITING BACTEREMIA AND BACTERIAL DISSEMINATION GOYERT SANNA M (US) 1997-01-03 WO disclosed
EP-0745095-A1 PEPTIDES RECOGNIZED BY MELANOMA-SPECIFIC CYTOTOXIC LYMPHOCYTES, AND USES THEREFOR THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 1996-12-04 EP disclosed
US-5508384-A NEUROLEPTIC AGENTS WITH REDUCED SIDE EFFECTS NEW YORK UNIVERSITY (US) 1996-04-16 US disclosed
WO-1995022561-A2 PEPTIDES RECOGNIZED BY MELANOMA-SPECIFIC CYTOTOXIC LYMPHOCYTES, AND USES THEREFOR UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 1995-08-24 WO disclosed
WO-1995013828-A1 BENEFICIAL WOUND HEALING APPLICATIONS OF CALRETICULIN AND OTHER HYALURONAN-ASSOCIATED PROTEINS NEW YORK UNIVERSITY (US) 1995-05-26 WO disclosed
WO-1995013291-A1 NEURON-GLIA CELL ADHESION MOLECULE, NG-CAM, IN TREATMENT OF NERVE DAMAGE NEW YORK UNIVERSITY (US) 1995-05-18 WO disclosed
WO-1994003601-A2 CLONING, EXPRESSION AND USES FOR NEUROCAN AS A CHONDROITIN SULFATE PROTEOGLYCAN NEW YORK UNIVERSITY (US) 1994-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12023316-B2 FAP-activated therapeutic agents, and uses related thereto FAP, FIBP, GOT1 KDM4E 2409/4885HPGD 1655/4885ALDH1A1 749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.