SCHEMBL8858271

SCHEMBL8858271

CCOc1ccc([Si](C)(C)COCc2cccc(Oc3ccccc3)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.46
KCNH2 Q12809 1/20 0.41
KDM4E B2RXH2 4/20 0.36
NPC1 O15118 4/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
ALDH1A1 P00352 3/20 0.36
RAB9A P51151 3/20 0.36
TP53 P04637 2/20 0.36
HPGD P15428 2/20 0.36
MAPT P10636 3/20 0.34
RELA Q04206 1/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
MAPK1 P28482 2/20 0.34
POLB P06746 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
RAD52 P43351 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7169249 0.89 KCNH2 (0.41) KCNH2KDM4ENPC1SMN1; SMN2ALDH1A1
SCHEMBL10551981 0.81 LTA4H (0.46) LTA4HKCNH2KDM4ENPC1SMN1; SMN2
SCHEMBL204914 0.79 LTA4H (0.51) LTA4HKDM4ESMN1; SMN2ALDH1A1TP53
SCHEMBL9560672 0.78 LTA4H (0.42) LTA4HKCNH2KDM4ENPC1SMN1; SMN2
SCHEMBL9560885 0.78 LTA4H (0.42) LTA4HKCNH2KDM4ENPC1SMN1; SMN2
SCHEMBL10360884 0.77 LTA4H (0.41) LTA4HKCNH2KDM4ENPC1SMN1; SMN2
SCHEMBL27690318 0.76 KCNH2 (0.53) LTA4HKCNH2NPC1SMN1; SMN2ALDH1A1
SCHEMBL9560742 0.76 LTA4H (0.40) LTA4HKCNH2KDM4ENPC1ALDH1A1
SCHEMBL9560684 0.76 LTA4H (0.40) LTA4HKCNH2KDM4ENPC1SMN1; SMN2
SCHEMBL7934880 0.75 LTA4H (0.49) LTA4HKCNH2KDM4ENPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0562164-B1 Emulsifier-free water dilutable concentrate or agent for preserving wood and woody materials DESOWAG MATERIALSCHUTZ GMBH (DE) 1997-08-13 EP claimed
EP-0458061-B1 Agent for preserving wood and wooden materials DESOWAG MATERIALSCHUTZ GMBH (DE) 1995-10-11 EP claimed
EP-0562164-A1 Emulsifier-free water dilutable concentrate or agent for preserving wood and woody materials DESOWAG GmbH (DE) 1993-09-29 EP claimed
US-5196407-A Fungicide, stabilizer, diluent DESOWAG MATERIALSCHUTZ GMBH (DE) 1993-03-23 US claimed
US-5196407-A Fungicide, stabilizer, diluent DESOWAG MATERIALSCHUTZ GMBH (DE) 1993-03-23 US disclosed