SCHEMBL7169249

SCHEMBL7169249

C[Si](C)(COCc1cccc(Oc2ccccc2)n1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.41
F2 P00734 3/20 0.34
F10 P00742 3/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
ST14 Q9Y5Y6 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MAP4K4 O95819 1/20 0.33
CYP1A2 P05177 3/20 0.33
CYP2C9 P11712 3/20 0.33
CYP2C19 P33261 3/20 0.33
HPGD P15428 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPK1 P28482 2/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8858271 0.89 LTA4H (0.46) KCNH2L3MBTL1SMN1; SMN2HPGDALDH1A1
SCHEMBL27690318 0.83 KCNH2 (0.53) KCNH2F2F10PRSS1PRSS2
SCHEMBL7922531 0.78 KCNH2 (0.45) KCNH2F2F10PRSS1PRSS2
SCHEMBL8373995 0.78 KCNH2 (0.47) KCNH2F2F10PRSS1PRSS2
SCHEMBL6856754 0.77 KCNH2 (0.44) KCNH2F2F10PRSS1PRSS2
SCHEMBL7934880 0.76 LTA4H (0.49) KCNH2F2F10PRSS1PRSS2
SCHEMBL10361436 0.75 KCNH2 (0.41) KCNH2F2F10PRSS1PRSS2
SCHEMBL250451 0.74 KDM4E (0.46) SMN1; SMN2CYP1A2CYP2C9CYP2C19HPGD
SCHEMBL10361286 0.74 KCNH2 (0.44) KCNH2F2F10PRSS1PRSS2
SCHEMBL9682509 0.74 KCNH2 (0.41) KCNH2F2F10PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0884149-A2 Microbicidal agents BAYER AG (DE) 1998-12-16 EP claimed
EP-0458061-B1 Agent for preserving wood and wooden materials DESOWAG MATERIALSCHUTZ GMBH (DE) 1995-10-11 EP claimed
EP-0458060-B1 Agent for preserving wood and wooden materials DESOWAG MATERIALSCHUTZ GMBH (DE) 1995-10-11 EP claimed
US-5196407-A Fungicide, stabilizer, diluent DESOWAG MATERIALSCHUTZ GMBH (DE) 1993-03-23 US claimed
EP-0458060-A1 Agent for preserving wood and wooden materials DESOWAG GmbH (DE) 1991-11-27 EP claimed
EP-0458061-A1 Agent for preserving wood and wooden materials DESOWAG GmbH (DE) 1991-11-27 EP claimed
EP-3088384-A1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF Merial, Inc. (US) 2016-11-02 EP disclosed
EP-1014792-B1 SYNERGISTIC COMPOSITIONS COMPRISING IMAZALIL AND EPOXICONAZOLE JANSSEN PHARMACEUTICA NV (BE) 2003-06-04 EP disclosed
US-6521653-B2 Microbicides in crop protection BAYER AKTIENGESELLSCHAFT (DE) 2003-02-18 US disclosed
US-20020107398-A1 Benzotriazoles ASSMANN LUTZ (DE) 2002-08-08 US disclosed
US-6380225-B1 AS MICROBICIDES IN CROP PROTECTION AND IN MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 2002-04-30 US disclosed
US-20020026059-A1 Benzimidazole derivatives ASSMANN LUTZ (DE) 2002-02-28 US disclosed
EP-0835256-B1 MICROBICIDAL BENZOTRIAZOLES BAYER AG (DE) 2002-01-02 EP disclosed
EP-0597336-A1 Use of furancarboxamides for the protection of materials BAYER AG (DE) 1994-05-18 EP disclosed
EP-0584461-A1 5-Haloimidazoles BAYER AG (DE) 1994-03-02 EP disclosed
EP-0571857-A1 Thiosemicarbazides BAYER AG (DE) 1993-12-01 EP disclosed
EP-0559002-A1 Cyanoalkene derivatives, method for their preparation and their use as microbiocides for protecting materials BAYER AG (DE) 1993-09-08 EP disclosed
US-5196407-A Fungicide, stabilizer, diluent DESOWAG MATERIALSCHUTZ GMBH (DE) 1993-03-23 US disclosed
EP-0458061-A1 Agent for preserving wood and wooden materials DESOWAG GmbH (DE) 1991-11-27 EP disclosed
EP-0458060-A1 Agent for preserving wood and wooden materials DESOWAG GmbH (DE) 1991-11-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020026059-A1 Benzimidazole derivatives BAK1, XDH, ZFX KCNH2 745/4885F2 2819/4885F10 1181/4885
US-20020107398-A1 Benzotriazoles HAX1, XDH, MLX KCNH2 2308/4885F2 1971/4885F10 455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.