Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8859587 | 0.86 | BBOX1 (0.34) | RAD52BBOX1 | |
| Hydrochloric Acid SCHEMBL27958932 | 0.80 | DNM1 (0.39) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL8859544 | 0.78 | KDM4E (0.38) | DNM1 | |
| Hydrochloric Acid SCHEMBL336333 | 0.77 | CYP3A4 (0.41) | DNM1KMT2ABBOX1 | |
| SCHEMBL28230537 | 0.77 | TSHR (0.40) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| SCHEMBL4228555 | 0.77 | DNM1 (0.40) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL10722105 | 0.77 | CYP3A4 (0.41) | DNM1KMT2ABBOX1 | |
| SCHEMBL4332483 | 0.75 | TSHR (0.36) | DNM1 | |
| Water SCHEMBL3302970 | 0.75 | DNM1 (0.39) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| SCHEMBL4952576 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637740-A | Production of 2, 3-epoxypropyl trialkyl ammonium chlorides | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1997-06-10 | — | — | US | disclosed |