Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4228555 | 0.97 | DNM1 (0.40) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL14957656 | 0.86 | CYP3A4 (0.32) | TSHR | |
| Hydrochloric Acid SCHEMBL27958899 | 0.84 | BBOX1 (0.37) | RAD52BBOX1TSHRPSMD14PLA2G1B | |
| SCHEMBL14958464 | 0.83 | TSHR (0.32) | HTTHSP90AA1TSHRPSMD14PLA2G1B | |
| Hydrochloric Acid SCHEMBL28151661 | 0.82 | DNM1 (0.42) | DNM1HTTHSP90AA1RAD52TSHR | |
| SCHEMBL28230537 | 0.81 | TSHR (0.40) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL8859622 | 0.80 | DNM1 (0.36) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Water SCHEMBL3302970 | 0.79 | DNM1 (0.39) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| SCHEMBL4230927 | 0.79 | DNM1 (0.44) | DNM1HTTHSP90AA1RAD52TSHR | |
| Hydrochloric Acid SCHEMBL27959033 | 0.76 | KDM4E (0.42) | DNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103045224-B | Preparation method of viscous oil viscosity reducer containing quaternary ammonium salt structure | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-10-01 | — | — | CN | claimed |