Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 6/20 | 0.34 |
| ▸ | TK2 | O00142 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294848 | 0.92 | ALDH1A1 (0.34) | ALDH1A1NPSR1TK1TK2 | |
| SCHEMBL9229159 | 0.89 | LMNA (0.35) | LMNA | |
| SCHEMBL28293078 | 0.88 | TK1 (0.32) | ALDH1A1NPSR1TK1TK2 | |
| SCHEMBL9218584 | 0.82 | P2RY2 (0.40) | — | |
| SCHEMBL888124 | 0.80 | TK1 (0.37) | ALDH1A1NPSR1TK1POLB | |
| SCHEMBL8744204 | 0.78 | TK1 (0.40) | ALDH1A1TK1TK2LMNAALB | |
| SCHEMBL261290 | 0.77 | TK1 (0.33) | TK1TK2 | |
| SCHEMBL7065023 | 0.76 | TK1 (0.33) | TK1TK2 | |
| SCHEMBL28293120 | 0.75 | LMNA (0.36) | TK1TK2LMNAADRA1A | |
| SCHEMBL1738254 | 0.75 | TK1 (0.31) | TK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455339-A | Method for the preparation of 2',3'-dideoxy and 2',3'-dideoxydide-hydro nucleosides | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1995-10-03 | — | — | US | disclosed |