Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487924 | 0.84 | CASP6 (0.51) | CASP6KMT2APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL8860183 | 0.80 | CASP6 (0.51) | CASP6SLC6A2CYP19A1HPGD | |
| SCHEMBL8860233 | 0.75 | CYP19A1 (0.43) | KMT2ASMN1; SMN2ALDH1A1MEN1CYP19A1 | |
| SCHEMBL7486935 | 0.70 | CASP6 (0.51) | CASP6CYP19A1 | |
| SCHEMBL7479829 | 0.70 | CASP6 (0.51) | CASP6KMT2AMEN1 | |
| SCHEMBL7476799 | 0.70 | ALDH1A1 (0.51) | CASP6KMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5986263 | 0.69 | HSD17B10 (0.47) | CASP6CHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL8418434 | 0.69 | ALDH1A1 (0.49) | CASP6KMT2ASMN1; SMN2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL8418433 | 0.69 | ALDH1A1 (0.49) | CASP6KMT2ASMN1; SMN2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7482266 | 0.68 | ALDH1A1 (0.48) | CASP6KMT2ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686626-A | COGNITION ACTIVATORS | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5621116-A | CHEMICAL INTERMEDIATES; MEMORY ENHANCERS FOR TREATMENT OF ALZHEIMER*S, ANALGESICS, ANTICONVULSANTS | HOECHST MARION ROUSSEL, INC. (US) | 1997-04-15 | — | — | US | disclosed |
| US-5464846-A | Learning enhancement, Alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0415102-B1 | 1,3-Dihydro-1-(pyridinylamino)-2H-indol-2-ones, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5179119-A | Cognition activators; alzheimer*s disease | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-01-12 | — | — | US | disclosed |
| US-5053511-A | Analgesics; anticonvulsants; treatment for alzheimers disease | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-10-01 | — | — | US | disclosed |
| US-5006537-A | Analgesics, memory enhancement, Alzheimer* disease | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0415102-A1 | 1,3-Dihydro-1-(pyridinylamino)-2H-indol-2-ones, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-03-06 | — | — | EP | disclosed |