Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186770 | 0.79 | DUT (0.44) | KIF11ALDH1A1RECQLDUTNR1H2 | |
| SCHEMBL4186763 | 0.79 | DUT (0.44) | KIF11ALDH1A1RECQLDUTNR1H2 | |
| SCHEMBL8860746 | 0.73 | CYP1A2 (0.36) | ALDH1A1RECQLDUT | |
| SCHEMBL26439425 | 0.72 | PLA2G2A (0.42) | KIF11DUTNR1H2NR1H3 | |
| SCHEMBL7776041 | 0.71 | TSHR (0.41) | ALDH1A1 | |
| SCHEMBL7001869 | 0.69 | KIF11 (0.44) | KIF11ALDH1A1 | |
| SCHEMBL4192567 | 0.69 | DUT (0.39) | KIF11DUT | |
| SCHEMBL4192561 | 0.69 | DUT (0.39) | KIF11DUT | |
| SCHEMBL3510726 | 0.68 | CA1 (0.50) | — | |
| SCHEMBL30046912 | 0.67 | CA1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997018809-A1 | PROTEIN KINASE C INHIBITOR | ELI LILLY AND COMPANY (US) | 1997-05-29 | — | — | WO | disclosed |