Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273493 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP2C19NPC1RAB9AHTR2C | |
| SCHEMBL5806586 | 0.83 | GPR119 (0.39) | CYP2C19 | |
| SCHEMBL5806582 | 0.83 | GPR119 (0.39) | CYP2C19 | |
| SCHEMBL14879565 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2C19NPC1RAB9AHTR2C | |
| SCHEMBL2843333 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP2C19NPC1RAB9AHTR2C | |
| SCHEMBL2727664 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP2C19NPC1RAB9AHTR2C | |
| SCHEMBL27486429 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP2C19NPC1RAB9AHTR2C | |
| SCHEMBL12128032 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP2C19NPC1RAB9AHTR2C | |
| SCHEMBL598928 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2C19NPC1RAB9AHTR2C | |
| SCHEMBL598929 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2C19NPC1RAB9AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677466-A | TESTING USING A AMIDINOPHENYL CONTAINING COMPOUND | DR. KARL THOMAE, GMBH (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5576444-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1996-11-19 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |