Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 8/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.38 |
| ▸ | KLK1 | P06870 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866762 | 0.85 | NPC1 (0.37) | WDR5ACACBACACA | |
| SCHEMBL8865835 | 0.84 | ACACB (0.49) | WDR5RORCACACBACACAEPHX2 | |
| SCHEMBL8867512 | 0.81 | GBA1 (0.34) | WDR5 | |
| SCHEMBL8866617 | 0.79 | ACACB (0.51) | ACACBACACA | |
| Trifluoroacetic Acid SCHEMBL8867001 | 0.77 | DPP4 (0.37) | WDR5KLKB1RORCHRH3 | |
| SCHEMBL8866110 | 0.77 | ACACB (0.41) | WDR5ACACBACACAHRH3 | |
| SCHEMBL8866094 | 0.74 | ACACB (0.45) | ACACBACACA | |
| SCHEMBL8866377 | 0.74 | ACACB (0.38) | ACACBACACAHRH3 | |
| SCHEMBL8866642 | 0.72 | RPS6KB1 (0.37) | WDR5HRH3 | |
| Trifluoroacetic Acid SCHEMBL8866732 | 0.70 | WDR5 (0.42) | WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |