Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9236233 | 0.94 | MAPT (0.46) | HPGDSMAPTGAASMN1; SMN2KDM4E | |
| Trifluoroacetic Acid SCHEMBL9230148 | 0.89 | HPGDS (0.41) | HPGDSGAASMN1; SMN2KDM4ENPC1 | |
| Trifluoroacetic Acid SCHEMBL8867217 | 0.88 | SUV39H2 (0.43) | MAPTITGB3ITGA2BDHFRGAA | |
| Trifluoroacetic Acid SCHEMBL8866136 | 0.86 | ITGB3 (0.49) | HPGDSMAPTITGB3ITGA2BDHFR | |
| Trifluoroacetic Acid SCHEMBL8866967 | 0.84 | ITGB3 (0.51) | HPGDSMAPTITGB3ITGA2BDHFR | |
| Trifluoroacetic Acid SCHEMBL8867174 | 0.84 | GPR6 (0.45) | HPGDSMAPTGAAHSD11B1APP | |
| SCHEMBL9236237 | 0.82 | ALDH1A1 (0.41) | HPGDSGAASMN1; SMN2KDM4ENPC1 | |
| Trifluoroacetic Acid SCHEMBL8866962 | 0.82 | ALDH1A1 (0.50) | HPGDSMAPTGAASMN1; SMN2KDM4E | |
| Trifluoroacetic Acid SCHEMBL8866457 | 0.79 | ITGB3 (0.47) | MAPTITGB3ITGA2BDHFRGAA | |
| Trifluoroacetic Acid SCHEMBL8867220 | 0.78 | ITGB3 (0.42) | MAPTITGB3ITGA2BDHFRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |