Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8866276 | 0.94 | HPGDS (0.43) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL9236237 | 0.87 | ALDH1A1 (0.41) | SMN1; SMN2GAAALDH1A1KDM4ENPC1 | |
| Trifluoroacetic Acid SCHEMBL9230148 | 0.82 | HPGDS (0.41) | SMN1; SMN2GAAALDH1A1KDM4ENPC1 | |
| Trifluoroacetic Acid SCHEMBL8867217 | 0.81 | SUV39H2 (0.43) | MAPTSMN1; SMN2GAAATR | |
| Trifluoroacetic Acid SCHEMBL8866136 | 0.80 | ITGB3 (0.49) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| Trifluoroacetic Acid SCHEMBL8866967 | 0.78 | ITGB3 (0.51) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| Trifluoroacetic Acid SCHEMBL8867174 | 0.77 | GPR6 (0.45) | MAPTGAAHPGDSALDH1A3HSD11B1 | |
| Trifluoroacetic Acid SCHEMBL8866962 | 0.74 | ALDH1A1 (0.50) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL8867330 | 0.74 | SUV39H2 (0.44) | MAPTSMN1; SMN2GAAALDH1A1NPC1 | |
| SCHEMBL8865883 | 0.74 | PRSS1 (0.53) | MAPTSMN1; SMN2GAAALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | claimed |