Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9236237 | 0.95 | ALDH1A1 (0.41) | HPGDSALDH1A1KDM4ENPC1POLB | |
| Trifluoroacetic Acid SCHEMBL8866276 | 0.89 | HPGDS (0.43) | HPGDSALDH1A1KDM4ENPC1POLB | |
| Trifluoroacetic Acid SCHEMBL9235973 | 0.88 | SUV39H2 (0.43) | LOXL2FFAR1HDAC4SUV39H2 | |
| Trifluoroacetic Acid SCHEMBL9233235 | 0.87 | HPGDS (0.42) | HPGDSALDH1A1KDM4ENPC1POLB | |
| Trifluoroacetic Acid SCHEMBL9229650 | 0.85 | HPGDS (0.42) | HPGDSALDH1A1KDM4ENPC1POLB | |
| SCHEMBL9236233 | 0.82 | MAPT (0.46) | HPGDSALDH1A1KDM4ENPC1POLB | |
| Trifluoroacetic Acid SCHEMBL8866962 | 0.80 | ALDH1A1 (0.50) | HPGDSALDH1A1KDM4ENPC1POLB | |
| Trifluoroacetic Acid SCHEMBL9233799 | 0.79 | HDAC4 (0.38) | SMN1; SMN2HDAC4PARP1PARP2 | |
| Trifluoroacetic Acid SCHEMBL9233271 | 0.78 | HDAC4 (0.36) | SMN1; SMN2HDAC4DPP4PARP1PARP2 | |
| Trifluoroacetic Acid SCHEMBL8867217 | 0.77 | SUV39H2 (0.43) | GAASMN1; SMN2HDAC4SUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |