Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 11/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | GNA11 | P29992 | 1/20 | 0.36 |
| ▸ | GNAQ | P50148 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8867001 | 0.90 | DPP4 (0.37) | WDR5DPP4DPP7GNA11GNAQ | |
| SCHEMBL8866343 | 0.73 | USP30 (0.46) | WDR5HPGDS | |
| SCHEMBL8866762 | 0.71 | NPC1 (0.37) | WDR5GNA11GNAQHPGDSNPC1 | |
| SCHEMBL8866637 | 0.70 | WDR5 (0.42) | WDR5 | |
| Trifluoroacetic Acid SCHEMBL8866757 | 0.68 | DHODH (0.46) | NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL8866836 | 0.67 | F11 (0.40) | WDR5DPP4DPP7HPGDSNPC1 | |
| Trifluoroacetic Acid SCHEMBL8866264 | 0.67 | F11 (0.39) | WDR5DPP4DPP7NPC1RAB9A | |
| SCHEMBL8867512 | 0.67 | GBA1 (0.34) | WDR5NPC1RAB9A | |
| SCHEMBL8866642 | 0.66 | RPS6KB1 (0.37) | WDR5GNA11GNAQ | |
| Trifluoroacetic Acid SCHEMBL6300559 | 0.65 | KMO (0.75) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |