Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.37 |
| ▸ | AKT1 | P31749 | 3/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | WDR5 | P61964 | 7/20 | 0.35 |
| ▸ | GNA11 | P29992 | 1/20 | 0.34 |
| ▸ | GNAQ | P50148 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867355 | 0.76 | CHRM1 (0.41) | WDR5 | |
| Trifluoroacetic Acid SCHEMBL8867001 | 0.75 | DPP4 (0.37) | RPS6KB1AKT1CHEK1WDR5GNA11 | |
| SCHEMBL8866762 | 0.75 | NPC1 (0.37) | CHEK1WDR5GNA11GNAQ | |
| SCHEMBL8867512 | 0.72 | GBA1 (0.34) | CHEK1WDR5ITGB3ITGA2B | |
| SCHEMBL8866617 | 0.72 | ACACB (0.51) | — | |
| SCHEMBL8866637 | 0.72 | WDR5 (0.42) | WDR5HRH3 | |
| SCHEMBL8866110 | 0.68 | ACACB (0.41) | WDR5GNA11GNAQHRH3 | |
| SCHEMBL8866094 | 0.67 | ACACB (0.45) | — | |
| SCHEMBL8866628 | 0.67 | GNA11 (0.37) | CHEK1WDR5GNA11GNAQHRH3 | |
| SCHEMBL8866485 | 0.67 | ACACB (0.42) | CHEK1WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |