Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 5/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867009 | 0.77 | HTR1A (0.37) | MTNR1AMTNR1BMAPTSMN1; SMN2KDM1A | |
| SCHEMBL7137898 | 0.75 | THRB (0.46) | ALDH1A1MAPTSMN1; SMN2KDM1A | |
| SCHEMBL11342932 | 0.75 | CYP2A6 (0.50) | ALDH1A1HTR1AHTR1DHTR2C | |
| SCHEMBL6613340 | 0.75 | PTPN1 (0.43) | KDM1AHTR1AHTR1DHTR2C | |
| SCHEMBL8950321 | 0.75 | CSNK2A1 (0.50) | ALDH1A1MAPTSMN1; SMN2HTR1AHTR1D | |
| SCHEMBL8168864 | 0.75 | ESR2 (0.47) | ALDH1A1LMNAMAPTHTR1AHTR1D | |
| SCHEMBL7756353 | 0.73 | TP53 (0.49) | MTNR1AMAPTSMN1; SMN2KDM1A | |
| SCHEMBL8161586 | 0.72 | MTNR1A (0.53) | MTNR1AMTNR1BALDH1A1LMNAMAPT | |
| SCHEMBL274259 | 0.71 | MAOB (0.49) | CYP2D6 | |
| SCHEMBL8869337 | 0.71 | MTNR1A (0.55) | MTNR1AMTNR1BMAPTSMN1; SMN2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703121-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-30 | — | — | US | disclosed |