Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868704 | 0.94 | P4HTM (0.48) | P4HTMLMNAMAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL8868529 | 0.92 | PPARA (0.49) | P4HTMLMNAMAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL8870501 | 0.91 | P4HTM (0.43) | P4HTMLMNAMAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL8868612 | 0.91 | P4HTM (0.45) | P4HTMLMNAMAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL7870557 | 0.89 | POLB (0.40) | P4HTMLMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL8868547 | 0.87 | P4HTM (0.47) | P4HTMLMNAMAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL8867585 | 0.87 | NLRP3 (0.57) | LMNAMAPTCYP3A4CYP2C9TSHR | |
| SCHEMBL8870423 | 0.87 | LMNA (0.48) | P4HTMLMNAMAPTSMN1; SMN2PPARA | |
| SCHEMBL8869375 | 0.85 | P4HTM (0.51) | P4HTMLMNAMAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL7874575 | 0.83 | MAPT (0.43) | P4HTMLMNAMAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |