Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | CCR4 | P51679 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869534 | 0.91 | PGR (0.53) | PGRFFAR1FFAR4MCL1CACNA1B | |
| SCHEMBL8869507 | 0.88 | CACNA1B (0.48) | PGRFFAR1FFAR4MCL1CACNA1B | |
| SCHEMBL8869093 | 0.87 | NR3C1 (0.52) | PGRSCN9ALMNA | |
| SCHEMBL8868644 | 0.84 | HTT (0.53) | CA1CA2GRM4KDM4ELMNA | |
| SCHEMBL8869092 | 0.84 | P4HTM (0.59) | MCL1CA12CA1CA2MMP2 | |
| SCHEMBL8869314 | 0.84 | POLB (0.55) | PGRFFAR1FFAR4MCL1CACNA1B | |
| SCHEMBL8869973 | 0.83 | CYP1A2 (0.46) | SCN9ALMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8868415 | 0.80 | SMN1; SMN2 (0.38) | LMNACYP3A4CYP2C9CYP2C19CCR2 | |
| SCHEMBL8868651 | 0.78 | HIF1A (0.46) | — | |
| SCHEMBL8868341 | 0.77 | CYP1A2 (0.45) | CACNA1BCA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |