Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | GCGR | P47871 | 5/20 | 0.43 |
| ▸ | FEN1 | P39748 | 3/20 | 0.42 |
| ▸ | EDNRA | P25101 | 2/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868209 | 0.86 | EGLN1 (0.45) | HIF1AEDNRAEDNRB | |
| SCHEMBL8869198 | 0.83 | POLB (0.47) | NAMPTFEN1EDNRAEDNRBALOX5AP | |
| SCHEMBL8869193 | 0.83 | P4HTM (0.54) | HIF1A | |
| SCHEMBL9574694 | 0.83 | MEN1 (0.47) | NAMPTFEN1EDNRAEDNRBALOX5AP | |
| SCHEMBL8869067 | 0.78 | PGR (0.53) | — | |
| SCHEMBL8868644 | 0.76 | HTT (0.53) | — | |
| SCHEMBL8747682 | 0.73 | EDNRA (0.47) | FEN1EDNRAEDNRBALOX5AP | |
| SCHEMBL8869169 | 0.73 | ALKBH2 (0.54) | FEN1ALOX5AP | |
| SCHEMBL9574709 | 0.73 | FEN1 (0.40) | NAMPTFEN1EDNRAEDNRBALOX5AP | |
| SCHEMBL21379406 | 0.72 | NAMPT (0.48) | HIF1ANAMPTGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |