Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870393 | 0.86 | P4HTM (0.49) | P4HTMAGTR2AGTR1 | |
| SCHEMBL8867590 | 0.85 | P4HTM (0.72) | P4HTMKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL7869169 | 0.84 | GABRA5 (0.44) | P4HTMAGTR2AGTR1 | |
| SCHEMBL8869169 | 0.83 | ALKBH2 (0.54) | AGTR2AGTR1 | |
| SCHEMBL9142936 | 0.83 | P4HTM (0.55) | P4HTMKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8868651 | 0.83 | HIF1A (0.46) | HIF1A | |
| SCHEMBL8870283 | 0.82 | P4HTM (0.52) | P4HTMHIF1ANPC1RAB9A | |
| SCHEMBL9515762 | 0.81 | P4HTM (0.49) | P4HTMNPC1RAB9AAGTR2AGTR1 | |
| SCHEMBL9139287 | 0.81 | P4HTM (0.52) | P4HTMKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL9139283 | 0.80 | P4HTM (0.49) | P4HTMAGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |