Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH2 | Q6NS38 | 9/20 | 0.54 |
| ▸ | ALKBH3 | Q96Q83 | 9/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.51 |
| ▸ | ALKBH5 | Q6P6C2 | 5/20 | 0.50 |
| ▸ | FEN1 | P39748 | 3/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868423 | 0.87 | ALKBH2 (0.52) | ALKBH2ALKBH3FTOALKBH5KMT2A | |
| SCHEMBL7867915 | 0.85 | ALKBH2 (0.40) | ALKBH2ALKBH3FTOALKBH5FEN1 | |
| SCHEMBL8869193 | 0.83 | P4HTM (0.54) | AGTR1AGTR2 | |
| SCHEMBL8869198 | 0.83 | POLB (0.47) | ALKBH2ALKBH3FTOALKBH5FEN1 | |
| SCHEMBL10738335 | 0.81 | ALKBH2 (0.47) | ALKBH2ALKBH3FTOALKBH5KAT6A | |
| SCHEMBL8869095 | 0.79 | ALKBH2 (0.57) | ALKBH2ALKBH3FTOALKBH5 | |
| SCHEMBL8945334 | 0.77 | POLB (0.54) | FTOALKBH5KMT2A | |
| SCHEMBL7869169 | 0.75 | GABRA5 (0.44) | AGTR1AGTR2 | |
| SCHEMBL8868651 | 0.73 | HIF1A (0.46) | FEN1ALOX5AP | |
| SCHEMBL5209853 | 0.73 | ROCK2 (0.52) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |