SCHEMBL886978

SCHEMBL886978

Nc1ccn(S(=O)(=O)O)c(=O)n1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.37
THRB P10828 1/20 0.37
MTOR P42345 1/20 0.37
MDM2 Q00987 1/20 0.37
NCOA1 Q15788 1/20 0.37
NCOA3 Q9Y6Q9 1/20 0.37
PDE3A Q14432 3/20 0.35
CACNA1F O60840 2/20 0.35
ALB P02768 2/20 0.35
MAPT P10636 2/20 0.35
CACNA1D Q01668 2/20 0.35
CACNA1S Q13698 2/20 0.35
CACNA1C Q13936 2/20 0.35
CRBN Q96SW2 1/20 0.35
FGFR1 P11362 2/20 0.35
PDE4D Q08499 1/20 0.35
SLC29A1 Q99808 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.34
KDM4E B2RXH2 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8743705 0.84 CRBN (0.36) LMNATHRBMTORMDM2NCOA1
SCHEMBL7016369 0.81 HTR6 (0.37) LMNATHRBMTORMDM2NCOA1
SCHEMBL24672711 0.74 CRBN (0.32) LMNATHRBMTORMDM2NCOA1
SCHEMBL7016019 0.73 L3MBTL1 (0.50) LMNAMAPTCRBNL3MBTL1HTR6
SCHEMBL22016090 0.69
SCHEMBL25378286 0.69
SCHEMBL11894064 0.69
SCHEMBL8790826 0.67
SCHEMBL8944773 0.67
SCHEMBL19692381 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250091048-A1 METHODS AND COMPOSITIONS FOR DETECTING GENETIC MATERIAL BIO-RAD LABORATORIES, INC. 2025-03-20 US disclosed
US-12097495-B2 Methods and compositions for detecting genetic material BIO-RAD LABORATORIES, INC. (US) 2024-09-24 US disclosed
CN-117089607-A Single cell RNA m 5 Analysis method for C modification 中国科学院北京基因组研究所(国家生物信息中心) 2023-11-21 CN disclosed
WO-2023217214-A1 METHOD FOR ANALYZING RNA M5C MODIFICATION IN SINGLE CELLS 中国科学院北京基因组研究所(国家生物信息中心) 2023-11-16 WO disclosed
US-20220362764-A1 METHODS AND COMPOSITIONS FOR DETECTING GENETIC MATERIAL BIO-RAD LABORATORIES, INC. (US) 2022-11-17 US disclosed
US-20220157469-A1 METHODS OF PREDICTING AGE, AND IDENTIFYING AND TREATING CONDITIONS ASSOCIATED WITH AGING USING SPECTRAL CLUSTERING AND DISCRETE COSINE TRANSFORM SERAGON PHARMACEUTICALS, INC. 2022-05-19 US disclosed
US-20220136037-A1 METHODS OF PREDICTING AGE, AND IDENTIFYING AND TREATING CONDITIONS ASSOCIATED WITH AGING SERAGON PHARMACEUTICALS, INC. 2022-05-05 US disclosed
US-20140357497-A1 DESIGNING PADLOCK PROBES FOR TARGETED GENOMIC SEQUENCING NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2014-12-04 US disclosed
US-20140295445-A1 Method for the Carry-Over Protection in DNA Amplification Systems Targeting Methylation Analysis Achieved by a Modified Pre-Treatment of Nucleic Acids EPIGENOMICS AG (DE) 2014-10-02 US disclosed
US-8753810-B2 Method for the carry-over protection in DNA amplification systems targeting methylation analysis achieved by a modified pre-treatment of nucleic acids EPIGENOMICS AG (DE) 2014-06-17 US disclosed
EP-1659186-B1 A method for the carry-over protection in DNA amplification systems targeting methylation analysis achieved by a modified pre-treatment of nucleic acids EPIGENOMICS AG (DE) 2008-05-21 EP disclosed
WO-2008047234-A1 A MOLECULE FOR PROVIDING A STANDARD FOR THE QUANTITATIVE ANALYSIS OF THE METHYLATION STATUS OF A NUCLEIC ACID EPIGENOMICS AG (DE) 2008-04-24 WO disclosed
US-20080096199-A1 Protecting preferential amplification products via cytosine sulfonation; using methylation pattern to diagnose disease EPIGENOMICS AG (DE) 2008-04-24 US disclosed
US-20080064043-A1 Method for detecting a methylation pattern EPIGENOMICS AG (DE) 2008-03-13 US disclosed
EP-1882746-A2 Method for detecting a methylation pattern Epigenomics AG (DE) 2008-01-30 EP disclosed
EP-1882747-A1 A method for the analysis of the methylation status of a nucleic acid Epigenomics AG (DE) 2008-01-30 EP disclosed
WO-2008009365-A2 A METHOD FOR DETERMINING THE METHYLATION RATE OF A NUCLEIC ACID EPIGENOMICS AG (DE) 2008-01-24 WO disclosed
WO-2007141034-A1 CARRY-OVER PROTECTION IN ENZYME-BASED DNA AMPLIFICATION SYSTEMS TARGETING METHYLATION ANALYSIS EPIGENOMICS AG (DE) 2007-12-13 WO disclosed
US-20060115835-A1 Protecting preferential amplification products via cytosine sulfonation; using methylation pattern to diagnose disease EPIGENOMICS AG (DE) 2006-06-01 US disclosed
EP-1659186-A1 A method for the carry-over protection in DNA amplification systems targeting methylation analysis achieved by a modified pre-treatment of nucleic acids Epigenomics AG (DE) 2006-05-24 EP disclosed