Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016369 | 0.78 | HTR6 (0.37) | CRBNFGFR1LMNATHRBMTOR | |
| SCHEMBL8743705 | 0.77 | CRBN (0.36) | CRBNFGFR1LMNATHRBMTOR | |
| SCHEMBL886978 | 0.74 | LMNA (0.37) | CRBNFGFR1LMNATHRBMTOR | |
| SCHEMBL7015200 | 0.70 | ALDH1A1 (0.36) | CRBN | |
| SCHEMBL7016019 | 0.70 | L3MBTL1 (0.50) | CRBNLMNA | |
| SCHEMBL10047082 | 0.68 | LMNA (0.35) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL27952255 | 0.65 | PIK3CB (0.41) | CRBNFGFR1LMNATHRBMTOR | |
| SCHEMBL19929 | 0.65 | — | — | |
| SCHEMBL16978939 | 0.65 | FGFR1 (0.42) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL3654078 | 0.64 | LMNA (0.47) | CRBNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237747-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | 四川海思科制药有限公司 | 2022-11-17 | — | — | WO | disclosed |