Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654078 | 0.81 | LMNA (0.47) | CA1CA2MEN1KMT2ANOD1 | |
| SCHEMBL7013936 | 0.77 | L3MBTL1 (0.46) | L3MBTL1CA1CA2MAPTRAPGEF4 | |
| SCHEMBL7016774 | 0.77 | KDM4E (0.50) | L3MBTL1CA1CA2GAAALDH1A1 | |
| SCHEMBL7016369 | 0.76 | HTR6 (0.37) | L3MBTL1MEN1KMT2AMAPTPOLB | |
| SCHEMBL8743705 | 0.76 | CRBN (0.36) | MAPTCRBNHTR6LMNA | |
| SCHEMBL7010844 | 0.75 | CA1 (0.55) | L3MBTL1CA1CA2MEN1KMT2A | |
| SCHEMBL12900477 | 0.75 | MEN1 (0.45) | L3MBTL1CA1CA2MEN1KMT2A | |
| SCHEMBL7014244 | 0.75 | MEN1 (0.48) | L3MBTL1CA1CA2MEN1KMT2A | |
| SCHEMBL886978 | 0.73 | LMNA (0.37) | L3MBTL1MAPTCRBNHTR6LMNA | |
| SCHEMBL1932978 | 0.73 | L3MBTL1 (0.54) | L3MBTL1CA1CA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877022-B1 | Sulfonylpyrimidine derivatives with anticancer activity | RUDJER BOSKOVIC INST (HR) | 2003-04-16 | — | — | EP | claimed |
| EP-0877022-A1 | Synthesis of the sulfonylpyrimidine derivatives with anticancer activity | Herbos d.d. (HR) | 1998-11-11 | — | — | EP | claimed |
| EP-0877022-B1 | Sulfonylpyrimidine derivatives with anticancer activity | RUDJER BOSKOVIC INST (HR) | 2003-04-16 | — | — | EP | disclosed |
| EP-0877022-A1 | Synthesis of the sulfonylpyrimidine derivatives with anticancer activity | Herbos d.d. (HR) | 1998-11-11 | — | — | EP | disclosed |