Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 4/20 | 0.44 |
| ▸ | HTR1B | P28222 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870342 | 0.90 | SCN9A (0.46) | HTR1DHTR1BKMT2ASCN9AHTR1A | |
| SCHEMBL8869627 | 0.90 | HTR2B (0.51) | HTR1DHTR1BKMT2AMEN1HTR1A | |
| SCHEMBL8868849 | 0.84 | SCN9A (0.43) | HTR1DHTR1BKMT2AMEN1SCN9A | |
| SCHEMBL8868679 | 0.82 | TRPV1 (0.42) | HTR1DHTR1BKMT2ASCN9AHTR1A | |
| SCHEMBL8869895 | 0.79 | CYP2D6 (0.44) | HTR1DHTR1BKMT2AMEN1HTR1A | |
| SCHEMBL23927939 | 0.76 | HTR2B (0.55) | HTR1DHTR1BKMT2AMEN1HTR1A | |
| Oxalic Acid SCHEMBL8870089 | 0.76 | KMT2A (0.73) | HTR1DHTR1BKMT2AHTR1AHTR2A | |
| SCHEMBL8868429 | 0.75 | GABRA1 (0.48) | KMT2AMEN1KDM4E | |
| SCHEMBL8869175 | 0.75 | HTR1D (0.70) | HTR1DHTR1BKMT2AHTR1AHTR2A | |
| SCHEMBL9208221 | 0.71 | HTR2A (0.44) | HTR1DHTR1BHTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637593-A | MIGRAINE; HYPOTENSIVE AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-06-10 | — | — | US | disclosed |