Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.42 |
| ▸ | HTR1D | P28221 | 5/20 | 0.40 |
| ▸ | HTR1B | P28222 | 4/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869627 | 0.83 | HTR2B (0.51) | TRPV1HTR1DHTR1BHTR1ATRPM8 | |
| SCHEMBL8870342 | 0.83 | SCN9A (0.46) | SCN9AHTR1DHTR1BHTR1ATACR1 | |
| SCHEMBL8868849 | 0.83 | SCN9A (0.43) | TRPV1SCN9AHTR1DHTR1BHTR1A | |
| SCHEMBL8870092 | 0.82 | HTR1D (0.44) | SCN9AHTR1DHTR1BHTR1ATRPM8 | |
| SCHEMBL8869706 | 0.80 | TRPM8 (0.47) | TRPV1HTR1DHTR1BHTR1ATRPM8 | |
| Oxalic Acid SCHEMBL8868671 | 0.79 | KMT2A (0.66) | HTR1DHTR1BHTR1ATRPM8MTNR1A | |
| SCHEMBL8870467 | 0.78 | HTR1D (0.61) | HTR1DHTR1BHTR1ATRPM8MTNR1A | |
| SCHEMBL9203858 | 0.74 | THRA (0.43) | TRPV1HTR1DHTR1BTRPM8PPARG | |
| SCHEMBL8868820 | 0.74 | TRPM8 (0.71) | HTR1DHTR1BHTR1ATRPM8LTA4H | |
| SCHEMBL8869895 | 0.74 | CYP2D6 (0.44) | HTR1DHTR1BHTR1AMTNR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637593-A | MIGRAINE; HYPOTENSIVE AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-06-10 | — | — | US | disclosed |