Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.46 |
| ▸ | HTR1D | P28221 | 4/20 | 0.45 |
| ▸ | HTR1B | P28222 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869627 | 0.91 | HTR2B (0.51) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL8870092 | 0.90 | HTR1D (0.44) | SCN9AHTR1DHTR1BHTR1AKMT2A | |
| SCHEMBL8868849 | 0.85 | SCN9A (0.43) | SCN9AHTR1DHTR1BHTR1AKMT2A | |
| SCHEMBL8868679 | 0.83 | TRPV1 (0.42) | SCN9AHTR1DHTR1BHTR1AKMT2A | |
| SCHEMBL8869895 | 0.80 | CYP2D6 (0.44) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL23927939 | 0.77 | HTR2B (0.55) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL8870437 | 0.76 | HTR1D (0.52) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL8868429 | 0.76 | GABRA1 (0.48) | KMT2AKDM4ETACR1LTA4HPLA2G2A | |
| Oxalic Acid SCHEMBL8870335 | 0.76 | KMT2A (0.75) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL8869593 | 0.74 | HTR1D (0.71) | HTR1DHTR1BHTR1AKMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637593-A | MIGRAINE; HYPOTENSIVE AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-06-10 | — | — | US | disclosed |