Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12643730 | 0.84 | ALDH1A1 (0.44) | ALDH1A1LMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL8870633 | 0.84 | RAB9A (0.46) | ALDH1A1LMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL8870630 | 0.84 | RAB9A (0.46) | ALDH1A1LMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL28360399 | 0.83 | LMNA (0.49) | ALDH1A1LMNAHTTHPGDL3MBTL1 | |
| SCHEMBL13925582 | 0.82 | USP2 (0.49) | ALDH1A1LMNAHTTHPGDL3MBTL1 | |
| SCHEMBL548010 | 0.82 | MTNR1A (0.43) | ALDH1A1LMNAHTTHPGDSMN1; SMN2 | |
| SCHEMBL28303700 | 0.82 | NLRP3 (0.35) | LMNAHPGDMEN1KMT2AUSP2 | |
| SCHEMBL8871572 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTHPGDL3MBTL1 | |
| SCHEMBL8871574 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTHPGDL3MBTL1 | |
| SCHEMBL6118230 | 0.80 | MAPT (0.41) | LMNASMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |