Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 5/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870992 | 0.91 | TSHR (0.47) | MPOSLC6A4ACHEHTR1ACDK4 | |
| SCHEMBL8871654 | 0.84 | MPO (0.59) | MPOSLC6A4HTR1ACDK4CCND1 | |
| SCHEMBL8870466 | 0.83 | HTR1A (0.63) | MPOSLC6A4HTR1A | |
| SCHEMBL8871409 | 0.80 | KMT2A (0.51) | KMT2ALMNAMPOSLC6A4GLA | |
| SCHEMBL8557211 | 0.79 | KMT2A (0.52) | KMT2ALMNAMPOSLC6A4GLA | |
| SCHEMBL18684485 | 0.74 | KMT2A (0.58) | KMT2ALMNAMPOSLC6A4GLA | |
| SCHEMBL11349537 | 0.73 | MPO (0.56) | KMT2ALMNAMPOSLC6A4ACHE | |
| SCHEMBL15148792 | 0.72 | MPO (0.59) | KMT2AMPOSLC6A4HTR1A | |
| SCHEMBL8870996 | 0.71 | TSHR (0.47) | SLC6A4ACHEHTR1A | |
| SCHEMBL15245439 | 0.70 | MPO (0.56) | KMT2ALMNAMPOSLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693655-A | 3-indolylpiperidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-02 | — | — | US | disclosed |