Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MPO | P05164 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870996 | 0.91 | TSHR (0.47) | SLC6A4HTR1AHTR7KCNH2ACHE | |
| SCHEMBL8557211 | 0.85 | KMT2A (0.52) | KMT2ALMNAMPOGLASLC6A4 | |
| SCHEMBL8871656 | 0.84 | MPO (0.59) | MPOSLC6A4HTR1AHTR7KCNH2 | |
| SCHEMBL8870468 | 0.83 | HTR1A (0.64) | MPOSLC6A4HTR1AHTR7KCNH2 | |
| SCHEMBL8871407 | 0.80 | KMT2A (0.48) | KMT2ALMNAMPOGLASLC6A4 | |
| SCHEMBL8870741 | 0.78 | TSHR (0.50) | KMT2AMPOSLC6A4MEN1HTR1A | |
| SCHEMBL11349537 | 0.77 | MPO (0.56) | KMT2ALMNAMPOSLC6A4HTR1A | |
| SCHEMBL8557474 | 0.75 | HSD11B1 (0.48) | SLC6A4HTR1AHTR7KCNH2HSD11B1 | |
| SCHEMBL8872021 | 0.75 | HTR2A (0.55) | MPOSLC6A4HTR1AHTR7KCNH2 | |
| SCHEMBL18684485 | 0.74 | KMT2A (0.58) | KMT2ALMNAMPOGLASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693655-A | 3-indolylpiperidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-02 | — | — | US | disclosed |