Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871527 | 0.83 | HSD11B1 (0.47) | MEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL9970976 | 0.80 | MAPK14 (0.37) | OPRM1ALDH1A1MAPK14CYP1A2MEN1 | |
| SCHEMBL9937345 | 0.80 | OPRM1 (0.39) | OPRM1ALDH1A1MAPK14CYP1A2MEN1 | |
| SCHEMBL11541268 | 0.72 | OPRM1 (0.43) | OPRM1ALDH1A1CYP1A2MEN1LMNA | |
| SCHEMBL9363341 | 0.70 | OPRM1 (0.37) | OPRM1ALDH1A1MAPK14MEN1LMNA | |
| SCHEMBL6993857 | 0.70 | GAA (0.40) | OPRM1ALDH1A1CYP1A2MEN1LMNA | |
| SCHEMBL14638776 | 0.70 | LMNA (0.46) | OPRM1ALDH1A1CYP1A2MEN1LMNA | |
| SCHEMBL7845042 | 0.69 | CA1 (0.46) | CYP2C9CYP2C19 | |
| SCHEMBL14061841 | 0.68 | TDP2 (0.44) | ALDH1A1CYP1A2MEN1LMNAMAPT | |
| SCHEMBL17211803 | 0.68 | TDP2 (0.44) | ALDH1A1CYP1A2MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591729-A | INSECTICIDES, PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-07 | — | — | US | disclosed |
| EP-0530264-B1 | ARTHROPODICIDAL TETRAHYDROPYRIDAZINES | DU PONT (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5380718-A | Arthropodicidal fused tetrahydropyridazines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0530264-A1 | ARTHROPODICIDAL TETRAHYDROPYRIDAZINES. | DU PONT (US) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991017983-A1 | ARTHROPODICIDAL TETRAHYDROPYRIDAZINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-11-28 | — | — | WO | disclosed |