Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1820807 | 0.81 | CA12 (0.69) | MTNR1A | |
| SCHEMBL14241869 | 0.80 | MTNR1A (0.72) | MTNR1A | |
| SCHEMBL18932186 | 0.79 | CA1 (0.57) | — | |
| SCHEMBL17205863 | 0.78 | CA1 (0.62) | — | |
| SCHEMBL11950523 | 0.77 | CA2 (0.48) | — | |
| SCHEMBL23417624 | 0.76 | ALDH1A1 (0.58) | — | |
| SCHEMBL25707013 | 0.76 | SMN1; SMN2 (0.65) | MTNR1A | |
| SCHEMBL13761515 | 0.76 | ALOX5 (0.46) | — | |
| SCHEMBL26037611 | 0.75 | GABRA1 (0.55) | — | |
| SCHEMBL10957439 | 0.75 | MTNR1A (0.49) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604261-A | HAVING HYDROXYL/ALKOXYL GROUP ORTHO TO AMIDE GROUP ON PHENYL RING; HIGH MELATONIN RECEPTOR AFFINITY | ADIR ET COMPAGNIE (FR) | 1997-02-18 | — | — | US | claimed |
| EP-0591057-B1 | Arylalkyl(thio)amides with melatonine receptor selectivity and process for their preparation | ADIR (FR) | 1996-07-10 | — | — | EP | claimed |
| EP-0591057-A1 | Arylalkyl(thio)amides with melatonine receptor selectivity and process for their preparation | ADIR ET COMPAGNIE (FR) | 1994-04-06 | — | — | EP | claimed |